apalutamide will reduce the extent or impact of modafinil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Coadministration of apalutamide, a strong CYP3A4 inducer, with medicines that happen to be CYP3A4 substrates may lead to decrease exposure to those remedies.Through this customized approach, he found out h

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